Full Research Professor
Laboratory for Molecular Biology (LMB)

Institute of molecular genetics and genetic engineering (IMGGE),
University of Belgrade

Vojvode Stepe 444a, 11042 Belgrade 152, Serbia
Mobile: +381 64  397 66 58                       
Phone: +381 11 397 66 58
Fax:     +381 11 397 58 08
E-mail: aleksni@imgge.bg.ac.rs

EDUCATION

2010 - PhD in Molecular Genetics and Genetic Engineering, Faculty of Biology (FB), UB
(Structural and functional analysis of smad4 gene 5' regulatory region in human pancreatic cancer)
2002 - M.Sc. in Molecular Genetics and Genetic Engineering, FB, UB
2000 - B.Sc. in Molecular Biology and Physiology, FB, University of Belgrade

RESEARCH EXPERIENCE

2021 - Full Research Professor, LMB, IMGGE
2016 - 2021 - Associate Research Professor, LMB, IMGGE
2010 - 2016 - Assistant Research Professor, LMB, IMGGE
2002 - 2010 - Research Assistant LMB, IMGGE
2000 - 2002 - Postgraduate Fellow of the Ministry of Science, Republic of Serbia

CAREER HISTORY

2000 - LMB, IMGGE

RESEARCH INTEREST

Molecular basis and pharmacogenetics of malignant gastrointestinal diseases
Transforming growth factor beta (TGFB) signaling pathway
Genetic risk factors in gastrointestinal and lung diseases
Development of methods for noninvasive molecular diagnostics

OTHER ACTIVITIES

2020-2022 - Principal Investigator of the project SENSOGENE (Science Fund of the Republic of Serbia)
2018-2022 - Science Communication Manager of the COST Action CA17118 TRANSCOLONCAN
since 2010 - Head of the Biology and Chemistry Program for high school students in IMGGE
2017-2019 - Lecturer in Academic Skills, PhD program of the Faculty of Biology,UB
2015-2017 - President of the Scientific Committee of the Belgrade International Molecular Life Science Conference for Students
2015-2016 - Member of the Program Council of the Center for the Promotion of Science
2014 - President of the Organizing Committee at the National Championship of Research Papers for high school students
2014 - Vice President of the Organizing Committee at the International Conference for Young
2012-2013 - Coordinator of the Researchers’ Night project SCIMFONICOM

SELECTED PUBLICATIONS

Ugrin M, Dinic J, Jeremic S, Dragicevic S, Banovic Djeri B, Nikolic A. Bacterial Nanocellulose as a Scaffold for In Vitro Cell Migration Assay. Nanomaterials. 2021;11:2322.

Despotovic J, Dragicevic S, Nikolic A. Effects of Chemotherapy for Metastatic Colorectal Cancer on the TGF-β Signaling and Related miRNAs hsa-miR-17-5p, hsa-miR-21-5p and hsa-miR-93-5p. Cell Biochem Biophys. 2021. doi: 10.1007/s12013-021-00980-3.

Bogdanovic A, Despotovic J, Galun D, Rosic J, Bidzic N, Nikolic A, Krivokapic Z. Prognostic Significance of CDH1, FN1 and VIM for Early Recurrence in Patients with Colorectal Liver Metastasis after Liver Resection. Cancer Manag Res. 2021;13:163–171.

Prosenc Zmrzljak U, Kosir R, Krivokapic Z, Radojkovic D, Nikolic A. Detection of somatic mutations with ddPCR from liquid biopsy of colorectal cancer patients. Genes 2021;12:289.

Dragicevic S, Milosevic M, Nestorovic B, Nikolic A. Influence of the Polymorphism C-509T in the TGFB1 Gene Promoter on the Response to Montelukast. Pediatr Aller Imm Pul. 2017;30(4):239-245.

Nikolic A, Ristanovic M, Zivaljevic V, Rankov AD, Radojkovic D, Paunovic I. SMAD4 gene promoter mutations in patients with thyroid tumors. Exp Mol Pathol. 2015; 99(1): 100-103.

Nikolic A, Cacev T, Aralica G, Popovic Hadzija M, Kapitanovic S, Radojkovic D. Mononucleotide repeats in the SMAD4 gene promoter in colon carcinoma tissue of Croatian patients. Exp Mol Pathol. 2015; 98(2): 133-135.

Vancevska A, Nikolic A. Method for assessment of deoxyribonuclease activity in biological samples. Lab Medicine 2013; 44(2): 125-128

Nikolic A, Ristanovic M, Perovic V, Trifunovic J, Perovic M, Radojkovic D. Genetic Alterations in SMAD4 and K-ras in Serbian Patients With Endometrial Carcinoma. Int J Gynecol Cancer. 2012; 22(3): 442-446.

Nikolic A, Kojic S, Knezevic S, Krivokapic Z, Ristanovic M, Radojkovic D. Structural and functional analysis of SMAD4 gene promoter in malignant pancreatic and colorectal tissues: detection of two novel polymorphic nucleotide repeats. Cancer Epidemiol 2011; 35(3): 265-271.